Product codes0575 propylene glycol revision date 08jan2016 4. Food and drug administration fda under 21 cfr x184. Uses advised against food, drug, pesticide or biocidal product use. Other names for propylene glycol are 1,2dihydroxypropane, 1,2propanediol, methyl glycol, and trimethyl glycol.
Safety data sheet ethylene glycol deep south chemical, inc. It is a propylene oxidebased diether and is hygroscopic attracts water. Chemical product and company identification product id. Back to top product description1,5 propylene glycol methyl ether pgme is a clear, colorless liquid with an ether odor.
Safety data sheet propylene glycol usp wizard labs. Skin contact wash off immediately with soap and plenty of water removing all contaminated clothes and shoes. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. An expert panel convened by the ntps center for the evaluation of risks to human reproduction concluded 23 that developmental and reproductive risks stemming from exposure to the chemicals propylene glycol and ethylene glycol are negligible. Solvent for inks and coatings use of the substancemixture. Propylene oxide reacts with water to produce propylene glycol 57556, dipropylene glycol, tripropylene glycol. Dipropylene glycol methyl ether, mixture of isomers. Tolerance exemptions beina reassessed in this document residues listed in 40 cfr 180.
In a rabbit study with thiophanate methyl, slight skeletal variations and decreased fetal weights were observed at doses that were also toxic to mother animals. Propylene glycol monomethyl ether acetate reagentplus. This material safety data sheet msds is issued by the supplier in accordance with national standards and guidelines. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.
Pma is a relatively fastevaporating, lowviscosity solvent. The propylene glycol in the feed corresponded to a dose of 2. Identification of the substancemixture and of the companyundertaking 1. Show this safety data sheet to the doctor in attendance. Dowanol dpm, dipropylene glycol monomethyl ether cas number 34590948. Propylene glycol monomethyl ether acetate recommended use laboratory chemicals. Table 5 gives a breakdown by percentage for the principal uses of propylene glycol in the united states. In general, glycols are nonirritating, have very low volatility and very low toxicity. Dow manufactures and sells pma and other propylene oxidebased glycol ethers under the trade name dowanoltm glycol ethers.
Dipropylene glycol mono methyl ether cas no 34590948 material safety data sheet sdsmsds section 1. Have victim rinse mouth with water, then give one to two glasses of water to drink. The atsdr toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Alternate name1methoxy2propanol, propylene glycol monomethyl ether, pgme, pm descriptionmethyl proxitol is a colourless, hygroscopic solvent with a volatility, viscosity and solvent power similar to those of ethylene oxidebased glycol ethers, e. Propylene glycol monomethyl ether acetate monument chemical. Propylene glycol intended for human use is designated as usp grade and is commonly found in foods, pharmaceuticals. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032. Rats fed diets containing 050,000 ppm of propylene glycol for 15 weeks. Never give anything by mouth to an unconscious person. Other pertinent literature is also presented, but is described in less detail than the key studies.
Propylene glycol methyl ether pgme or 1methoxy2propanol is an organic solvent with a wide variety of industrial and commercial uses. In a series of animal studies, propylene glycol was not a developmental toxicant. Propylene glycol methyl ether acetate pgmea formula. Ethylene glycol can cause central nervous system depression and metabolic acidosis. It is miscible with a broad range of solvents, including water, acetone, and chloroform. Due to missing tests no recommendation to the glove material can be given for the product the preparation the chemical mixture. September 22, 2016 the dow chemical company page 2 of 6 manufacture of product6 capacity the dow chemical company has been producing propylene glycols since 1942. Propylene glycol monomethyl ether acetate, pma material uses. Physical and chemical properties oxidizing properties vapor pressure relative density octanolwater partition coefficient. Product and company identification product name propylene glycol monomethyl ether acetate others name esters, n. Ethylene glycol mono butyl ether material safety data sheet. Identification of the substancemixture and of the companyundertaking. Read the product manufacturers material safety data.
Find msds or sds, a coa, data sheets and more information. Pdf synthesis of propylene glycol methyl ether catalyzed. Safety glasses with sideshields use splash goggles when eye contact due to splashing or spraying liquid is possible. Propylene glycol is a compound which is generally recognized as safe gras by the u. Handling and storage protect container from physical damage. Polyalkylene glycol monobutyl ether pgme for handling. Propylene glycol is also present in propylene glycol alginate, which is known as e405. Process propylene glycol methyl ether is produced by the reaction of propylene oxide with methanol using a catalyst as shown below.
Identification of the substance and of the companyundertaking trade name. The dow chemical company dow manufactures this product under the trade name proglyde dmm glycol diether. Similar to other glycol ethers, it is used as a carriersolvent in printingwriting inks and paints coatings. Material safety data sheet validation date product and company identification 1. The available toxicity database for dpgme consists. Exposures to propylene glycol having no adverse effects on the mother. Protective gloves the glove material has to be impermeable and resistant to the product the substance the preparation. Tetramethylguanidinebased ionic liquids were used as effective catalysts for the synthesis of propylene glycol methyl ether from methanol and propylene oxide. Store in a cool, dry, ventilated area aw ay from sources of heat, moisture, and incompatible substances. Pseries glycol ethers are propylene oxidebased, more hydrophobic, have lower surface tension and lower toxicity, and work well in higher ph systems. Page 5 of 7 msds mono propylene glycol skin protection. Propylene glycol is clear, colorless, slightly syrupy liquid at room temperature.
Ch3chohch2oh material safety data sheet chemical name. Page 1 of 10 msds t di propylene glycol material safety data sheetmsds dipropylene glycol 1. Di propylene glycol methyl ether, mixture of isomers. Hold eye open and rinse slowly and gently with water for 15 to 20 minutes. It is miscible with water and many organic solvents and has the formula c. Wear protective gloves and clean bodycovering clothing. Propylene glycol is an organic compound with the chemical formula ch3chohch2oh.
Pdf synthesis of propylene glycol methyl ether catalyzed by. The four isomers are not separated nor produced as individual chemicals. Propylene glycol ethers acetates 108656 1methoxy2propyl acetate, meproxac, mpa, pma methyl proxitol acetate is a colourless, neutral propylene oxidebased glycol ether acetate with a mild odour and a volatility, viscosity and solvent power similar to those of ethylene glycol based glycol ether acetates. Multiphase equilibria of binary and ternary mixtures. In the mouse, propylene glycol was not a reproductive toxicant. Dipropylene glycol dimethyl ether dpgdme is a colorless liquid with a mild odor. Propylene glycol 57556 99 oral ld50 rat 20000 mgkg dermal ld50 rabbit 20800 mgkg note. Paints, ink solvent, detergent, leather dyeing, pesticides materials. Propylene glycol is an aliphatic dihydric alcohol with a wide range of applications in the food industry such as an anticaking agent, antioxidant, humectant, flavoring agent, emulsifier, stabilizer, thickener etc. Details of the supplier of the safety data sheet emergency telephone number for information us call. Dipropylene glycol monomethyl ether mixture of isomeres for synthesis. It is miscible with water and many organic solvents and has the formula c 3 h 8 o 2. Msds for any workplace product that contains a hazardous substance, and must make the msds. Page 5 of 10 msds t di propylene glycol personal protective equipment hand protection.
It is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Ethylene glycol cas no 107211 material safety data sheet sdsmsds. Ethylene glycol material safety data sheet cas no 107. Inert reassessment dipropylene glycol monomethyl ether. Maintain eye wash fountain and quickdrench facilities in wo rk area. Extreme high moderate low section 1 chemical product and company identification product name polypropylene glycol statement of hazardous nature considered a hazardous substance according to osha 29 cfr 1910. Pm glycol ether propylene glycol methyl ether no 8. Recycle solvent if possible if local regulations permit, may be put in sanitary landfill, may be incinerated in approved facility after mixing with a suitable flammable waste.
Material safety data sheet propylene glycol usp kosher december 2, 2009 page 4 of 5 disposal considerations waste disposal. Propylene glycol, food and flavor ingredient, fema no 2940. Methyl glycol also known as 2methoxyethanol, glycol monomethyl ether, ethylene glycol monomethylether, methyl cellosolve, methyl oxito, and mgl is a clear, colourless liquid that has a mild characteristic, etherlike, odour. Material safety data sheet nr02460 propylene glycol 1. Ethylene glycol industrialethylene glycol meglobal glycol solv ethylene glycol, section 4. November 22, 2015 2the dow chemical company page of 5 manufacture of product3 capacity western europe is the largest producer and consumer of propylene oxidebased glycol ethers. General description 1methoxy2propanol propylene glycol methyl ether, pgme, a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of znmgal zincmagnesiumaluminium catalysts.
Dow and its global affiliates annually manufacture approximately 900,000 metric tons 1. Safety data sheet according to federal register vol. Its degradation by microorganisms in different soil types has been investigated. The dow chemical company dow produces propylene oxidebased glycol. Product safety assessment proglyde dmm glycol diether. Dipropylene glycol monomethyl ether dpgme, cas reg. The reassessment decision is to maintain each of the two inert tolerance exemptions asis. Chemical product and company identification product name. Propylene glycol is unique among the glycols in that it is safe for humans to take internally. Identification of the substance or mixture and of the supplier trade name.
Polypropylene glycol sc255443 hazard alert code key. Firstaid measures description of first aid measures do not induce vomiting. Identification of the substance monopropylene glycol cas number 57556 alternative names 1. Dipropylene glycol monomethyl ether cas 34590948 818533. Similar to other glycol ethers, it is used as a carriersolvent in printingwriting inks and paintscoatings. November 28, 2015 the dow chemical company page 5 of 6 propylene glycol ethers, sids initial assessment report for 17 siam, organisation for economic cooperation and development, arona, italy, november 1114, 2003. Methyl di glycol also known as diethylene glycol monomethyl ether, diglycol monomethyl ether, methoxy diglycol, ethylene diglycol monomethyl ether, degme, mdg and mdge is a clear, colourless, almost odourless liquid which has the formula c 5 h 12 o 3. Regulations and this msds material safety data sheet contains all the information required by the cpr. Nonfood use dowanol pma glycol ether propylene glycol methyl ether. First aid measures first aid measures eye contact rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Recommended use and restrictions on use use of the substancemixture. Propylene glycol methyl ether acetate pma is a colorless liquid with an etherlike odor. Dipropylene glycol methyl ether acetate safety data sheet according to federal register vol.
Page 1 of 7 dipropylene glycol mono methyl ether cas no 34590948 material safety data sheet sds msds section 1. Containing two alcohol groups, it is classed as a diol. Do not use combustible materials, such as saw dust. Dowanol pm glycol ether is the fastest evaporating solvent in the dowanol glycol ether family.
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